On behalf of the whole team at Orchard, I would like to extend a humble thank you to all those that have participated in the MLD gene therapy clinical development program and to the broader MLD community who supported them throughout their journey.

The courage, commitment and resilience of the MLD community inspires us in our work every day. Orchard remains committed to MLD patients and families and will continue to work with a great sense of urgency, as we recognize the devasting impact this disease often has on families.

We also want to extend thanks to our partners at Fondazione Telethon and Ospedale San Raffaele, who have been instrumental in providing specialized care for some of the most complex and devastating health conditions.

We are excited about what the future may bring and the potential to open up new possibilities for people with rare inherited diseases.