Senior Manager, Medical Communications - Boston


Boston, Massachusetts, United States

Medical Affairs

Senior Manager, Medical Communications

Location: Boston, MA

Reporting to: Senior Director, Medical Communications

The Company:

Orchard Therapeutics is a leading global, fully integrated, commercial-stage biotech dedicated to transforming the lives of patients with rare diseases through innovative gene therapies.

Partnering with world-leading research institutions in gene therapy, Orchard’s portfolio of autologous ex vivo gene therapy programs has demonstrated sustained clinical benefit in over 150 patients across five disease areas. These programs include Strimvelis®, the first autologous ex vivo gene therapy approved by the EMA in 2016, 3 programs in advanced registrational studies in MLD (metachromatic leukodystrophy), WAS (Wiskott Aldrich syndrome) and ADA-SCID (adenosine deaminase severe combined immunodeficiency), 2 other clinical programs in X-CGD (X-linked chronic granulomatous disease) and beta-thalassemia, as well as an extensive preclinical pipeline

Orchard is a publicly traded company (NASDAQ: ORTX) with offices in the UK and the US, including London, San Francisco and Boston.

Job summary

The Sr. Manager, Medical Communications will be reporting to the Senior Director, Medical Communications. This role will be located in the company headquarters in Boston, MA (US). This is an ideal opportunity for an experienced Medical Writer or similar to work on a small, global team where he/she can make an impact and broaden their expertise in Medical Affairs. This role offers an unparalleled opportunity for exposure to multiple drug launches in multiple countries, in the rare disease space. As part of the medical affairs team, this role will have a real and timely impact on the education of therapies with the potential to transform patients’ lives.

Key Elements and Responsibilities

Under the guidance of the Senior Director, Medical Communications, the successful candidate will:

  • Compliantly manage the implementation and tactical execution of high-visibility publications (manuscripts, abstracts, presentations) per the Publication Plan
  • Create and manage the tactical execution of materials (e.g., slide decks, FAQs) for field medical personnel per the Medical Communications Plan
  • Development of content for presentation at global scientific meetings (e.g., symposia)
  • Assistance with conference coverage and scheduling, including identification of important presentations and medical intelligence gathering
  • Perform regular literature surveillance, inform appropriate individuals about general literature of interest, and create detailed alerts upon identification of high interest new literature in a timely manner
  • Assist with regular medical, legal, regulatory approval meetings for externally-facing medical material
  • Assist in the development and maintenance of departmental processes, operations, policies, SOPs, and associated documents
  • Support medical affairs initiatives as needed and perform other related duties as required by position
  • Some travel may be required (<10% overall time)


Required knowledge

  • Significant, direct experience in Medical Communications/Medical Affairs at a pharmaceutical company or a medical/scientific communications agency ideally with some focus on Medical Writing and Publication Planning
  • Working knowledge and understanding of Good Publication Practices

Skills & Abilities

  • Excellent organizational skills and strong attention to detail; and ability to prioritize effectively and handle multiple tasks
  • Strong interpersonal skills including verbal and written communication are essential in this collaborative work environment and to interact efficiently with Key Opinion Leaders and Health Care Professionals
  • Ability to work in a global cross-functional environment
  • Adept at synthesizing and clearly communicating salient scientific data and messages
  • Experience with Datavision or other publication planning software a plus
  • Experience in rare disease/cell therapies/immunology a plus
  • Experience with vendor management a plus


  • M.S. or higher degree in a scientific discipline preferred

Orchard Therapeutics is an Equal Opportunity, Affirmative Action employer. Minorities, women, veterans, and individuals with disabilities are encouraged to apply.


The successful candidate will enjoy a competitive base salary and the opportunity to participate in incentive compensation programs, including a stock option plans. Orchard Therapeutics, Ltd. offers a comprehensive benefits program, including: medical, dental and vision care; paid vacation and holiday time; access to a voluntary 401(k). Orchard Therapeutics is an equal opportunity employer.


All employment offers and CV’s are managed through our Human Resources Department and all candidates are presented through this avenue. Therefore, the Human Resources Department at Orchard Therapeutics requests that recruiters are not to contact Orchard Therapeutics employees directly to present candidates. Complying with this request will be a factor in determining future professional relationships with Orchard Therapeutics. Orchard Therapeutics will not accept unsolicited resumes from any source other than directly from candidates for either current or future positions. Submission of unsolicited resumes in advance of an agreement between the Human Resources Department and the recruiter does not create any implied obligation on the part of Orchard Therapeutics.