London, England, United Kingdom
Orchard Therapeutics, Ltd. is a biotechnology company incorporated in September 2015 and dedicated to bringing transformative gene therapies to patients with serious and life-threatening rare diseases. This an exciting opportunity for a well-qualified candidate to join a rapidly growing international company focused on transforming the lives of patients through innovative gene therapies.
The Associate Director, Early-stage Cell Therapy Operations will oversee and coordinate the development, manufacture and delivery of Orchard Therapeutics innovative gene-modified cell-based therapeutic products in cooperation with a series of academic and CMO collaborators. The role will be focused on bringing commercial company expertise and support to a significant and wide-ranging academic collaboration from pre-clinical development to early clinical work.
Such activities will include process and assay development, cell therapy intermediate and drug product formulation and stability evaluation, raw material evaluation, process scale-up / scale-out, and validation of manufacturing processes and controls to support company’s product programs and alliances from pre-clinical research through to early-stage clinical trials.
This role is ideal for an experienced professional who is looking to work in a small team with high-level academic collaborators at the top of their field, whilst also working and engaging with the large and highly experienced commercial and clinical-stage CMC team at Orchard. The role may suit someone with cell therapy operations experience gained either in an academic GMP setting, a CMO or clinical-stage cell therapy company.
As a proven technical expert in the development, manufacture and delivery of cell-based therapy products with significant applied experience in the biotechnology industry, this candidate will possess:
Education and skills
All employment offers and CV’s are managed through our Human Resources Department and all candidates are presented through this avenue. Therefore, the Human Resources Department at Orchard Therapeutics requests that recruiters are not to contact Orchard Therapeutics employees directly to present candidates. Complying with this request will be a factor in determining future professional relationships with Orchard Therapeutics. Orchard Therapeutics will not accept unsolicited resumes from any source other than directly from candidates for either current or future positions. Submission of unsolicited resumes in advance of an agreement between the Human Resources Department and the recruiter does not create any implied obligation on the part of Orchard Therapeutics.